VOXZOGO (vosoritide) is specifically indicated for pediatric patients with achondroplasia who have open epiphyses (open bone growth plates).
Its primary use is to increase linear growth in this population.
Age: The drug is approved for use in children from age 5 years to adolescents (the study included patients aged 4.4 months to 15 years).
Essential Requirement: Patients must have open epiphyses confirmed by a healthcare provider. Treatment must be permanently discontinued once growth plates close.
Key Restriction: VOXZOGO is not recommended for patients with significant renal impairment (eGFR < 60 mL/min/1.73 m²).
Patients must also be able to follow administration requirements, including adequate food/fluid intake before the daily subcutaneous injection.

