VOXZOGO administration requires specific precautions to minimize the risk of adverse events, particularly hypotension.
Prior to VOXZOGO injection, patients must have adequate food and fluid intake to reduce the risk of transient hypotension, a known risk associated with the drug. Caregivers should be trained in proper preparation, administration, and disposal techniques. Injection sites should be rotated, and areas of erythema, swelling, or tenderness should be avoided. VOXZOGO is not recommended for patients with significant renal impairment (eGFR < 60 mL/min/1.73 m²). The drug should not be mixed with other medications, and unused portions must be discarded. Use in pregnancy, lactation, and other special populations is not specified in the description.

