Metyrapone is a widely used drug that can inhibit the production and release of adrenocorticotropic hormone, and can effectively treat paraadrenal insufficiency by controlling the production of cortisol.

Contraindications and precautions for Metyrapone

It is forbidden for those who are allergic to Metyrapone and adrenal insufficiency.

Patients with pituitary insufficiency and renal insufficiency should be used with caution.

Pregnant women have poor response to Metyrapone test, and the fetus can have a pituitary response to enzyme blockade.

Overdose of Metyrapone is easy to induce adrenal insufficiency, and hyperkalemia, hypochloremia or hyponatremia will occur when poisoning.

Metyrapone may cause dizziness and sedation. Patients should not drive or operate machinery until these effects have worn off.

Adverse effects of Metyrapone

The common adverse reactions of Metyrapone include nausea, vomiting, dizziness, hypertension and hypokalemic alkalosis.

Treatment of adverse reactions of Metyrapone

Nausea and vomiting: Try to avoid strenuous activity and give your body enough time to rest. Stay hydrated, avoid dehydration, and drink water or sugar-free electrolyte drinks frequently in small sips. Start with light, easy-to-digest foods and gradually increase the amount and variety of your diet.

Vertigo

Avoid irritating sounds and light and try to be quiet. Avoid sudden changes in position, especially when standing up from a lying or sitting position. Give enough rest to avoid excessive fatigue.

High blood pressure

Take your medication exactly as prescribed by your doctor and follow your doctor's treatment plan. Reduce sodium and increase your intake of fiber-rich foods, such as fruits, vegetables and whole grains. Reduce your intake of coffee, tea, caffeinated beverages, and alcohol.

Hypokalkalemia

Increase your intake of potassium-rich foods such as bananas, potatoes, spinach, etc. If the low potassium is caused by medications, talk to your doctor about possible adjustments or alternatives. Avoid long-term or excessive use of alkaline drugs to reduce the risk of alkaline poisoning.

For specific symptoms and conditions, it is advisable to consult a doctor for further evaluation and treatment. The doctor can give more accurate advice and treatment options based on your specific situation.

Price of Metyrapone

As of October 2023, Metyrapone has not been listed in mainland China, and hospital pharmacies in mainland China are not yet available, and there is no price announcement.

Patients in need can purchase it at a local hospital pharmacy with a local doctor's prescription. You can also buy this product under the guidance of a doctor, but it should be noted that it should be purchased from a regular and qualified hospital or pharmacy.