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What are the side effects of Metyrapone(Metopirone)?
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Article source: Seagull Pharmacy
Jun 25, 2025

The common side effects of Metyrapone(Metopirone) include high blood pressure, hypokalemic alkalosis, nausea, vomiting, dizziness, etc., and the patient's physique and condition will affect the side effects, and the side effects after medication are also different. Patients may also have side effects such as leukopenia, anemia, thrombocytopenia, dizziness, rash, headache, diarrhea, etc.

Side effects of Metyrapone (Metopirone)

The following adverse reactions associated with the use of Metyrapone(Metopirone) have been identified in clinical trials or post-marketing reports:

1. Cardiovascular system: hypotension;

2. Gastrointestinal system: abdominal discomfort or pain, nausea, vomiting;

3. Central nervous system: sedation, dizziness, headache;

4. Dermatological system: allergic rash;

5. Blood system: leukopenia, anemia and/or thrombocytopenia;

Measures to deal with the side effects of Metyrapone(Metopirone)

Nausea or vomiting

Try to avoid strenuous activities and ensure sufficient rest time. Hydrate, avoid dehydration, eat lightly, avoid greasy and irritating foods, and gradually increase the amount and variety of your diet.

Dizziness

Try to be quiet and avoid irritating sounds and light. Avoid sudden changes in body position, especially the position of the head and neck. If vertigo is severe or persistent, seek medical attention.

High blood pressure

pay attention to controlling emotions and avoid being too excited. Treatment with antihypertensive drugs under the guidance of a doctor.

Hypokalemic alkalosis

Diet should be adjusted, it is recommended to eat foods containing potassium and slightly higher chlorine, such as oranges, bananas, spinach, meat, etc., you can also eat some dried fruit foods, such as peanuts, walnuts, etc., and you can also drink some soups, such as chicken soup, fish soup, pork rib soup, etc., which can alleviate the symptoms of patients to a certain extent.

Headache

ensure sufficient rest time and avoid fatigue. It is also important to maintain emotional stability and use painkillers as prescribed by your doctor if necessary.

Allergic rash

patients should pay attention to keeping the skin clean and hygienic, avoid scratching, if the rash is accompanied by itching and other symptoms, under the guidance of the doctor, calamine lotion, loratadine and other drugs can be used to relieve discomfort.

Drowsiness and dizziness

It can usually be relieved by adjusting the dosage. It is advisable to consult a doctor and treat the symptoms under the guidance of a doctor, as if left untreated, may lead to limitations in daily activities or the occurrence of risky behaviors.

These are just some of the common treatments for Metyrapone(Metopirone), if symptoms are severe or persistent, seek medical attention and follow your doctor's advice.

Precautions for taking Metyrapone(Metopirone)

When deciding to use Metyrapone(Metopirone), you must weigh the risks and benefits of taking the drug.

If you have any abnormal or allergic reaction to Metyrapone(Metopirone) or any other drug, you must inform your doctor.

Metyrapone(Metopirone) may cause nausea and vomiting, especially when taken in large doses. Taking each dose with food or milk or immediately after a meal may lessen this effect.

Before any medical examination, please tell your treating doctor that you are taking Metyrapone(Metopirone). The results of some tests may be affected by the drug.

For different patients, the dose of Metyrapone(Metopirone) will be different. Follow your doctor's instructions or take your medications as prescribed.

If you miss a dose of this medicine, please take it as soon as possible. If it's almost time for your next dose, skip the missed dose and return to your regular medication schedule. Do not double the dose.

If you are taking Metyrapone(Metopirone) for testing but have missed a dose, please contact your doctor.

Note: For internal discussion among medical personnel only. For specific medication, please consult the attending physician. Drug information may change over time. For the latest information, we recommend adding a medical consultant or consulting for free online.
Metyrapone(Metopirone)
Metyrapone(Metopirone)
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