Ambrisentan is a drug used to treat pulmonary hypertension. It is an endothelin receptor antagonist that reduces pulmonary artery pressure by dilating blood vessels, thereby reducing the burden on the heart and improving patients' exercise capacity and quality of life.

What is Ambrisentan?

Ambrisentan, also known as Vanrick, is an effective drug for the treatment of pulmonary hypertension. Ambrisentan is an endothelin receptor antagonist that relaxes vascular smooth muscle and reduces pulmonary artery pressure by blocking the action of endothelin. Ambrisentan is mainly used to treat pulmonary hypertension with World Health Organization (WHO) grade II or III symptoms, helping patients improve their exercise capacity and delay clinical deterioration.

Drug types and uses

Ambrisentan is a tablet, usually with a starting dose of 5 mg taken orally on an empty stomach or after a meal, once a day. If the patient tolerates it well, the doctor may adjust the dose to 10mg once a day. The tablets need to be swallowed whole and cannot be split, crushed or chewed. Ambrisentan reduces pulmonary artery pressure by dilating blood vessels, thereby reducing the burden on the heart and improving patients' exercise capacity and quality of life.

Manufacturer and price

Ambrisentan is produced by Cipla Pharmaceuticals in India, with a specification of 5mg*10 tablets. The drug has been launched in China and included in the medical insurance catalog, providing economic convenience for patients.

After understanding the basic information of Ambrisentan, patients may be concerned about what the elderly need to pay attention to when using Ambrisentan. The metabolism of the elderly cannot be compared with that of young people, so more attention should be paid.

Precautions for the use of Ambrisentan tablets by the elderly

Due to the decline in physical function, the elderly should start with the minimum dose and adjust the dose according to individual conditions. The elderly often suffer from multiple diseases at the same time. When taking medicine, acute and severe diseases should be treated first, and other diseases should be taken into account after the condition stabilizes.

Principles and precautions for medication

The elderly should follow the doctor's instructions when using Ambrisentan tablets, start with a small dose, and adjust the dose according to tolerance and condition. Liver function and kidney function should be checked regularly during medication. The elderly should avoid using multiple drugs at the same time to avoid increasing the risk of adverse reactions.

Medication guidance for special populations

For elderly people who are old, light, and in poor physical condition, the dosage should be reduced as appropriate. Elderly people should be checked regularly to detect and deal with potential health problems in a timely manner.

During the long-term use of Ambrisentan, patients also need to pay attention to possible adverse reactions.

Adverse reactions of long-term use of Ambrisentan

Long-term use of Ambrisentan tablets may cause some adverse reactions. Liver damage is one of them, manifested as symptoms such as elevated transaminase and jaundice. Some people may develop allergic skin diseases such as urticaria and eczema. A small number of people may also experience anemia symptoms, such as pale complexion and mental fatigue.

Liver-related adverse reactions

Long-term use of Ambrisentan tablets may increase the burden on the liver and cause liver damage. Patients may experience symptoms such as elevated transaminase and jaundice. Liver function should be monitored regularly during medication, and if abnormalities are found, they should seek medical attention in a timely manner.

Other adverse reactions

In addition to liver damage, long-term use of Ambrisentan tablets may also cause allergic skin diseases, anemia, headaches, edema, hypotension, palpitations, gastrointestinal discomfort and other adverse reactions. Patients should pay attention to observe their physical reactions and seek medical attention in time if they feel uncomfortable.

Warm reminder: During the use of Ambrisentan tablets, patients should follow the doctor's instructions and take the medicine on time and in the right amount. Patients should pay attention to observe their physical reactions and seek medical attention in time if they feel uncomfortable. Patients should also maintain good living habits, such as a reasonable diet, moderate exercise and regular work and rest, to support the treatment effect.