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What are the side effects of Sandostatin?
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Article source: Seagull Pharmacy
Jul 22, 2025

Sandostatin is a biological agent for the treatment of diseases such as acromegaly. It can effectively inhibit hormone levels, delay tumor growth, improve preoperative indicators, reduce or eliminate the discomfort and pain caused by various complications, and thus improve the quality of life of patients.

What are the side effects of Sandostatin?

As an effective drug for the treatment of acromegaly, Sandostatin (octreotide) may cause some side effects. The following are the manifestations and treatment methods of common side effects:

1. Diarrhea

It is often manifested as continuous or frequent stools, which are usually soft or watery. If the diarrhea is mild, no special treatment is usually required. Maintain adequate water intake to avoid dehydration. If the diarrhea persists or worsens, it is recommended to report to the doctor in time, and treatment may need to be adjusted.

2. Cholelithiasis

The formation of stones in the gallbladder may cause abdominal pain or discomfort. If symptoms of gallstones occur, the doctor should be notified in time. The doctor may perform relevant examinations such as ultrasound to confirm the diagnosis. Treatment may include changes in dietary habits, medication, or surgical intervention if necessary.

3. Abdominal pain and bloating

The patient may experience abdominal discomfort or pain, as well as bloating. If the abdominal pain and bloating are mild, symptoms can be relieved by adjusting the diet and avoiding foods that cause bloating. If symptoms persist or worsen, it is recommended to consult a doctor and further evaluation may be required.

Patients should communicate with their doctors regularly during treatment with Sanlong and report any new symptoms or changes in symptoms. The doctor will adjust the treatment plan according to the patient's specific situation to ensure that the patient obtains the maximum treatment benefit while minimizing the occurrence of side effects. Understanding drug interactions is also very important for the patient's treatment and health.

Drug interactions of Sanlong

The following are situations in which Sanlong (octreotide) may interact with other drugs, as well as related precautions:

1. Cyclosporine

The simultaneous injection of Sanlong and cyclosporine may reduce the blood concentration of cyclosporine and increase the risk of transplant rejection. When patients need to receive Sanlong and cyclosporine at the same time, doctors should carefully monitor the patient's blood concentration of cyclosporine and adjust the dose as needed to ensure that adequate immunosuppression levels are maintained.

2. Insulin and oral hypoglycemic drugs

Octreotide can inhibit the secretion of insulin and glucagon, which may affect blood sugar levels. During treatment with Sanlong, the patient's blood sugar level should be closely monitored. The dose of insulin or oral hypoglycemic drugs may need to be adjusted to ensure good blood sugar control.

3. Bromocriptine

Giving octreotide and bromocriptine at the same time may increase the utilization of bromocriptine. When patients need to receive Sanlong and bromocriptine at the same time, doctors should pay attention to monitoring the patient's bromocriptine blood concentration and adjust the dose as needed. 

[Warm Tips] During any drug treatment, patients should tell their doctors about all drugs they are taking, including prescription drugs, over-the-counter drugs, and supplements. This helps doctors better understand the patient's overall drug status and avoid potential interactions and adverse reactions. Patients should make drug adjustments and management under the guidance of their doctors.

Note: For internal discussion among medical personnel only. For specific medication, please consult the attending physician. Drug information may change over time. For the latest information, we recommend adding a medical consultant or consulting for free online.
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