Agamree (Vamorolone) is an innovative therapeutic drug for Duchenne Muscular Dystrophy (DMD), which has attracted widespread attention worldwide. Since it has not yet been launched in China and is not included in China's national medical insurance scheme, patients and their families must exercise extra caution when seeking legitimate channels to purchase authentic Agamree. So, what are the legitimate channels for purchasing authentic Agamree?

Legitimate Channels for Purchasing Authentic Agamree

For domestic patients in China, purchasing Agamree directly through domestic hospitals or pharmacies is not feasible, as the drug has not been launched in the country.

Purchase Through Official Channels

The most direct and secure way is to purchase Agamree through the official website of Santhera Pharmaceuticals (the Swiss original manufacturer of Agamree) or its authorized international distributors. These channels usually provide detailed drug introductions, purchase guides, as well as payment and delivery methods.

Purchase from Formal Overseas Pharmacies

Another feasible method is to purchase the drug from formal overseas pharmacies. Patients can choose to buy Agamree from well-known pharmacies in countries where the drug has been launched (such as Germany, the United States, the United Kingdom, etc.). Before making a purchase, it is advisable to consult local pharmacists or doctors to understand the drug's applicability, dosage and administration, and potential risks.

Precautions for Agamree Administration

When using Agamree, patients and their families must strictly follow the doctor's instructions and pay attention to the following matters.

Dosage Adjustment and Administration Method

The recommended dosage of Agamree is 6mg/kg taken orally once a day, preferably with meals. For patients weighing more than 50kg, the maximum daily dosage should not exceed 300mg. Under special circumstances (such as impaired liver function, concurrent use with other drugs, etc.), the dosage may need to be adjusted appropriately.

Monitoring for Adverse Reactions

During the use of Agamree, adverse reactions such as Cushingoid-like changes, psychiatric and behavioral disorders, and gastrointestinal reactions may occur. Patients and their families should closely monitor the patient's physical condition; if any discomfort occurs, they should seek medical attention immediately and inform the doctor that the patient is taking Agamree.

Discontinuation and Dosage Tapering

If a patient needs to stop using Agamree, the dosage should be tapered off under the doctor's guidance to reduce the risk of adrenal insufficiency caused by sudden drug withdrawal. Do not discontinue the drug or suddenly change the medication regimen without authorization.

Dietary Precautions for Agamree Use

During the use of Agamree, patients also need to pay special attention to their diet to support drug treatment and improve therapeutic efficacy.

Balanced Nutrient Intake

Patients should maintain a balanced diet and consume sufficient protein, carbohydrates, fats, vitamins, and minerals. This helps maintain the patient's physical condition, enhance immunity, and reduce the risk of infection.

Avoid Stimulating Foods

During the use of Agamree, patients should try to avoid consuming stimulating foods such as spicy, greasy, and raw/cold foods. These foods may increase the burden on the gastrointestinal tract and affect the absorption and metabolism of the drug.

Patients should follow the doctor's guidance to arrange their diet reasonably and avoid adverse interactions between food and the drug.