Before taking Alpelisib(PIQRAY)

Important safety information and measures to mitigate risks.

Warnings and Considerations

Key precautions include the risk of severe hypersensitivity reactions requiring permanent discontinuation, the need to monitor for and manage severe skin reactions, and the critical importance of blood glucose monitoring before and during treatment due to the high risk of hyperglycemia. Patients should be advised of signs of pneumonitis, diarrhea, and embryo-fetal toxicity. Effective contraception is advised for patients of reproductive potential.