Before taking Xagrid(bictegravir/emtricitabine/tenofovir alafenamide)

Important precautions for BIKTARVY involve monitoring for hepatitis B flare-ups, drug interactions, and renal health.

Warnings and Precautions

Patients with HIV-1 and hepatitis B coinfection should be closely monitored for hepatic function after stopping BIKTARVY, as severe exacerbations can occur. Drug interactions are critical; coadministration with dofetilide or rifampin is contraindicated due to risks of toxicity or reduced efficacy. Regular assessment of serum creatinine and urine parameters is advised to detect renal impairment. Additionally, immune reconstitution syndrome may cause inflammatory responses to opportunistic infections. Healthcare providers should evaluate concomitant medications and avoid nephrotoxic a

gents to minimize risks.