


Reminder: The outer packaging is for reference only, please purchase and use under the guidance of a pharmacist. For read by medical and pharmaceutical professionals only.
This section summarizes the key characteristics of VESANOID.VESANOID (tretinoin) is an orally administered retinoid capsule indicated for the treatment of a specific form of leukemia.
Its active component, all-trans retinoic acid, functions by inducing cellular differentiation in malignant promyelocytes. It is specifically targeted for patients with confirmed genetic markers and requires careful clinical management due to its significant side effect profile and specific handling requirements.
1.Cutaneous Squamous Cell Carcinoma (CSCC): For metastatic or locally advanced disease not amenable to curative surgery or radiation.
2.Basal Cell Carcinoma (BCC): For locally advanced or metastatic disease after hedgehog pathway inhibitor therapy or when such therapy is not appropriate.
3.Non-Small Cell Lung Cancer (NSCLC):
In combination with platinum-based chemotherapy for first-line treatment in patients without EGFR, ALK, or ROS1 aberrations.
As monotherapy for first-line treatment in patients with high PD-L1 expression (TPS ≥50%) without EGFR, ALK, or ROS1 aberrations.
Administer as an intravenous infusion over 30 minutes.
CSCC and BCC: 350 mg every 3 weeks until disease progression, unacceptable toxicity, or up to 24 months.
NSCLC: 350 mg every 3 weeks until disease progression or unacceptable toxicity.
Dose modifications or discontinuation may be required based on severity of immune-mediated adverse reactions.
