Bylvay(Odevixibat) Side Effects

Treatment may lead to adverse reactions including diarrhea, liver test abnormalities, and abdominal pain.

Adverse Reactions

The most frequently reported adverse reactions for PFIC patients include diarrhea, liver test abnormalities (elevated transaminases, bilirubin), vomiting, abdominal pain, and fat-soluble vitamin deficiency. In ALGS patients, common adverse reactions are diarrhea, abdominal pain, hematoma, and weight decrease. Post-marketing reports have included gastrointestinal hemorrhage and elevated gamma-glutamyltransferase. Diarrhea was a common reason for temporary treatment interruption.