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Odevixibat(Bylvay)
Reminder: The outer packaging is for reference only, please purchase and use under the guidance of a pharmacist. For read by medical and pharmaceutical professionals only.
Bylvay(Odevixibat) Instructions:Uses,Dosage, Side Effects
BYLVAY contains the active ingredient odevixibat, a reversible inhibitor of the ileal bile acid transporter (IBAT). It is formulated as oral pellets and capsules for once-daily administration. This medication is specifically designed for pediatric patients, with its use supported by randomized, double-blind, placebo-controlled clinical trials. It functions by reducing the reabsorption of bile acids in the terminal ileum, which correlates with a reduction in serum bile acid levels and an improvement in pruritus severity.
Pruritus in patients with PFIC (3 months and older).
Cholestatic pruritus in patients with ALGS (12 months and older).
PFIC: Start with 40 mcg/kg once daily with morning meal; may increase to 120 mcg/kg daily if no improvement after 3 months.
ALGS: 120 mcg/kg once daily with morning meal.
Capsules should be swallowed whole; pellets may be mixed with soft food or liquid.
Avoid concurrent administration with bile acid binding resins within 4 hours.
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