The launch of the breast disease treatment drug ORSERDU/Elacestrant has brought new vitality to countless patients. This drug selectively degrades estrogen receptors and effectively blocks the growth path of lesion cells, becoming a highlight in the field of breast disease treatment. So, is the treatment effect of Elacestrant(ORSERDU)?

Is Elacestrant effective?

Elacestrant showed obvious therapeutic effects when treating patients with ER-positive and HER2-negative advanced breast diseases. The following is a detailed introduction to the therapeutic effects of Elacestrant:

1.EMERALD clinical trial

This is an open-label, multicenter, randomized controlled phase III clinical trial to evaluate the efficacy of Elacestrant in patients with ER-positive, HER2-negative advanced or metastatic breast disease. The trial results showed that among the 228 patients with ESR1 mutations, the median progression-free survival (PFS) in the Alaser group was 3.8 months, while the median PFS in the control group (SOC endocrine therapy group) was 1.9 months. Patients in the Ailas group had a 45% reduction in the risk of disease progression or death.

2.Real-world application data

In real-world drug use data, Elacestrant also showed good efficacy. One study analyzed 742 patients who used Elacestrant and showed that the next treatment regimen could be delayed by an average of 6.43 months, which means that the patient's lesion control time was significantly extended.

With its unique mechanism of action, good tolerance and FDA approval, Elacestrant provides strong support for its application in the field of breast disease treatment.

Elacestrant(ORSERDU) precautions

Elacestrant is a drug used to treat ER-positive, HER2-negative advanced or metastatic breast diseases. When using Elacestrant, patients need to pay attention to the following:

1.Comprehensive physical examination

Before starting the use of Elacestrant, patients should undergo a comprehensive physical examination, including liver and kidney function assessment, to assess the overall health of the patient.

2.Inform the medical history and medication status

Patients should inform their doctor of their complete medical history and current medication so that their doctor can evaluate whether the medication is suitable.

Elacestrant has obvious efficacy in treating patients with breast diseases, but the above things need to be paid attention to during use to ensure the effectiveness of the medication.