Elacestrant was developed and produced by Stemline, the United States, and was approved by the U.S. Food and Drug Administration (FDA) in January 2023, becoming the only oral selective estrogen receptor degrader(SERD) drug on the market. Elacestrant is not currently available in China. You can follow the National Food and Drug Administration or the relevant official website to learn about the drug information.

What is the therapeutic effect of Elacestrant?

Elacestrant is an innovative selective estrogen receptor degrader(SERD) that performs well in the treatment of advanced or metastatic breast diseases. It is especially suitable for postmenopausal female or adult male patients who are positive for estrogen receptor (ER), negative for human epidermal growth factor receptor 2 (HER2), and carry mutations in the estrogen receptor alpha gene (ESR1). By directly binding to estrogen receptors, Elacestrant induced its degradation, thereby effectively blocking estrogen signaling pathways, significantly prolonging the patient's progression-free survival (PFS) and improving overall survival (OS).

Elacestrant medication guidance?

In order to fully utilize the therapeutic effect of Elacestrant, patients must follow correct medication guidance.

Recommended dosage

The recommended dose of Elacestrant is 345 mg once a day, taken orally with food. Make sure to take the medication at the same time every day and swallow the whole tablet without chewing, crushing or splitting the tablets.

Things to note

If you miss taking the medication for more than 6 hours or vomiting occurs, please skip this medication and take the next dose at the scheduled time the next day. During the use of Elacestrant, patients may experience side effects such as fatigue, nausea, diarrhea and joint pain, but these symptoms are usually mild and tolerated.

Regular monitoring

Before and during the initiation of Elacestrant, patients should regularly monitor indicators such as blood lipids, liver function, and blood cell count, and promptly detect and deal with potential adverse reactions.

Correct medication guidance is crucial to the therapeutic effect of Elacestrant. Patients should follow the recommended dose and medication time, pay attention to potential side effects, and regularly monitor relevant indicators.

Elacestrant storage method?

In addition to clarifying the therapeutic effect of Elacestrant and understanding the medication guidance of Elacestrant, correct storage methods are also crucial to maintaining the efficacy of Elacestrant.

Storage temperature

Elacestrant should be stored in an environment of 20°C to 25°C (68°F to 77°F). The permissible temperature range is 15°C to 30°C (59°F to 86°F).

Avoid exposure

Ensure that Elacestrant is not exposed to high humidity and direct sunlight to prevent the drug from absorbing moisture, spoiling or breaking down the active ingredients.

Keep Elacestrant out of reach of children and keep the medication properly to avoid loss or misuse.